PT - JOURNAL ARTICLE AU - Florian S. Eichler AU - Paul Wang AU - Robert J. Wityk AU - Norman J. Beauchamp, Jr AU - Peter B. Barker TI - Diffuse Metabolic Abnormalities in Reversible Posterior Leukoencephalopathy Syndrome DP - 2002 May 01 TA - American Journal of Neuroradiology PG - 833--837 VI - 23 IP - 5 4099 - http://www.ajnr.org/content/23/5/833.short 4100 - http://www.ajnr.org/content/23/5/833.full SO - Am. J. Neuroradiol.2002 May 01; 23 AB - Summary: Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging. Widespread metabolic abnormalities, consisting of increased choline and creatine levels and mildly decreased N-acetylaspartate, occurred in regions with both normal and abnormal MR imaging appearances. In one case for which proton MR spectroscopic imaging follow-up was available, all metabolite levels had returned to normal by 2 months. Proton MR spectroscopic imaging may be helpful for the diagnosis and investigation of the underlying pathophysiology of reversible posterior leukoencephalopathy syndrome.