RT Journal Article
SR Electronic
T1 Increased Uptake of Technetium-99m-Hexamethylpropyleneamine Oxime Related to Primary Leptomeningeal Melanoma
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1404
OP 1406
VO 23
IS 8
A1 Takao Sagiuchi
A1 Katsumi Ishii
A1 Satoshi Utsuki
A1 Yuuji Asano
A1 Shinya Tsukahara
A1 Shinichi Kan
A1 Kiyotaka Fujii
A1 Kazushige Hayakawa
YR 2002
UL http://www.ajnr.org/content/23/8/1404.abstract
AB Summary: We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.