PT  - JOURNAL ARTICLE
AU  - Chung-Ping Lo
AU  - Cheng-Yu Chen
AU  - Shy-Chyi Chin
AU  - Chun-Jung Juan
AU  - Chun-Jen Hsueh
AU  - Ann Chen
TI  - Disappearing Calvarium in Gorham Disease: MR Imaging Characteristics with Pathologic Correlation
DP  - 2004 Mar 01
TA  - American Journal of Neuroradiology
PG  - 415--418
VI  - 25
IP  - 3
4099  - http://www.ajnr.org/content/25/3/415.short
4100  - http://www.ajnr.org/content/25/3/415.full
SO  - Am. J. Neuroradiol.2004 Mar 01; 25
AB  - Summary: Gorham disease is a rare condition characterized by intraosseous neoplastic proliferation of hemangiomatous tissue with progressive, massive osteolysis. We present a pathologically proved case of Gorham disease that involved the left parietal bone in a 23-year-old man. Imaging studies including conventional radiography of the skull, CT, MR imaging, and Technetium-99 m (Tc-99 m) scintigraphy demonstrated a large skull defect without associated soft tissue mass over the left parietal skull. Contrast enhancement and increased isotope uptake along the margin of the defect were shown at gadolinium-enhanced T1-weighted MR imaging and Tc-99 m methylene diphosphate (Tc-99 m MDP) bone scintigraphy. Pathologic study revealed intraosseous angiomatosis at the periphery of the osteolytic skull lesion.