TY - JOUR T1 - Influenza-Associated Encephalitis/Encephalopathy with a Reversible Lesion in the Splenium of the Corpus Callosum: A Case Report and Literature Review JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 798 LP - 802 VL - 25 IS - 5 AU - Jun-ichi Takanashi AU - A. James Barkovich AU - Ken-ichi Yamaguchi AU - Yoichi Kohno Y1 - 2004/05/01 UR - http://www.ajnr.org/content/25/5/798.abstract N2 - Summary: We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with a reduced apparent diffusion coefficient (ADC) value, which completely resolved on follow-up studies at day 10. We postulate two possible mechanisms for decreased ADC; namely, intramyelinic edema and an inflammatory infiltrate. ER -