%0 Journal Article %A Mika Kitajima %A Yukunori Korogi %A Masayuki Yamura %A Ichiro Ikushima %A Yoshiko Hayashida %A Yukio Ando %A Makoto Uchino %A Yasuyuki Yamashita %T Familial Amyloid Polyneuropathy: Hypertrophy of Ligaments Supporting the Spinal Cord %D 2004 %J American Journal of Neuroradiology %P 1599-1602 %V 25 %N 9 %X Summary: We describe characteristic spinal MR findings of two cases of familial amyloid polyneuropathy (FAP). Both cases showed leptomeningeal enhancement on contrast-enhanced T1-weighted image. In addition, three-dimensional constructive interference in steady-state imaging demonstrated thickening of the ligaments, other connective tissues within the spinal canal, dura matter, and dorsal nerve roots. These findings in FAP are felt to represent amyloid deposition. %U https://www.ajnr.org/content/ajnr/25/9/1599.full.pdf