TY - JOUR T1 - Three-Dimensional Color Doppler Sonography in Carotid Artery Stenosis JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1294 LP - 1299 VL - 24 IS - 7 AU - Robert A. Bucek AU - Markus Reiter AU - Albert Dirisamer AU - Markus Haumer AU - Angelika Fritz AU - Erich Minar AU - Johannes Lammer Y1 - 2003/08/01 UR - http://www.ajnr.org/content/24/7/1294.abstract N2 - BACKGROUND AND PURPOSE: Color Doppler sonography (CDS) suffers from such disadvantages as high interobserver variability and problems with data presentation and storage. We therefore performed a prospective trial to assess the role of three-dimensional CDS (3D-CDS) in the evaluation of internal carotid artery stenosis (ICAS).METHODS: We included 32 consecutive patients with sonographically verified ICAS (30–99%) and 16 asymptomatic volunteers. All underwent CDS and 3D-CDS, and 23 patients also underwent intraarterial angiography. The sensitivity, specificity, positive predictive value, and negative predictive value for the detection of high-grade ICAS were analyzed by three blinded readers, who also graded the percentage of ICAS.RESULTS: CDS revealed 14 patients with mild to moderate ICAS and 18 patients with high-grade ICAS. Mean sensitivity of 3D-CDS was 81.5%, mean specificity was 98.9%, mean positive predictive value was 97.9%, and mean negative predictive value was 89.9%. 3D-CDS correlated significantly with CDS (mean r = 0.85; P < .001) and angiography (mean r = 0.57; P = .01).CONCLUSION: 3D-CDS findings correlate with those obtained by CDS and angiography; 3D-CDS also offers excellent interobserver correlation, positive predictive value, and specificity, approaching 100% for the detection of high-grade ICAS. ER -