RT Journal Article
SR Electronic
T1 Neuro-Behcet’s Disease: Diffusion MR Imaging and Proton MR Spectroscopy
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1612
OP 1614
VO 24
IS 8
A1 R. Nuri Sener
YR 2003
UL http://www.ajnr.org/content/24/8/1612.abstract
AB Summary: We herein report the case of a 53-year-old woman with Behcet’s disease and an acute T2-hyperintense lesion in left side of the pons. Echo-planar “trace” diffusion MR imaging revealed high signal intensity changes at the lesion site on b = 1000 s/mm2 images, initially suggesting restricted diffusion. On corresponding apparent diffusion coefficient maps, however, the lesion had high signal intensity and high apparent diffusion coefficient values (1.22 × 10−3 mm2/s), compared with the contralateral normal side of the pons (0.86 × 10−3 mm2/s) and compared with the normal temporal white matter (0.80 × 10−3 mm2/s). This was consistent with the presence of increased diffusion, hence vasogenic edema. Proton MR spectroscopy excluded acute infarction. This particular pattern (high signal intensity on b = 1000 s/mm2 images in association with high apparent diffusion coefficient values) likely represented the acute inflammatory process associated with disrupted brain-blood barrier in the fulminant form of neuro-Behcet’s disease. Follow-up examinations ≤2 years later revealed a remaining gliotic lesion.