PT - JOURNAL ARTICLE AU - Kiminobu Yonemura AU - Yasuhiro Hasegawa AU - Kazumi Kimura AU - Kazuo Minematsu AU - Takenori Yamaguchi TI - Diffusion-weighted MR Imaging in a Case of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Strokelike Episodes DP - 2001 Feb 01 TA - American Journal of Neuroradiology PG - 269--272 VI - 22 IP - 2 4099 - http://www.ajnr.org/content/22/2/269.short 4100 - http://www.ajnr.org/content/22/2/269.full SO - Am. J. Neuroradiol.2001 Feb 01; 22 AB - Summary: In a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS), both T2- and diffusion-weighted MR imaging revealed lesions as hyperintense areas in the occipital lobes early after strokelike episodes. In these lesions, no significant reduction in apparent diffusion coefficient was noted. Apparent diffusion coefficient mapping may help to differentiate strokelike episodes in MELAS from acute ischemic stroke. The strokelike episodes may be related to vasogenic edema and hyperperfusion, which were suggested by our single-photon emission CT and MR imaging studies.