RT Journal Article
SR Electronic
T1 Evaluation of Pleomorphic Xanthoastrocytoma by Use of Positron Emission Tomography with [18-F]-Fluorodeoxyglucose and [11C]-Methionine Tracers
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 311
OP 313
VO 22
IS 2
A1 Naohiro Tsuyuguchi
A1 Yoshimi Matsuoka
A1 Ichiro Sunada
A1 Yasuhiro Matsusaka
A1 Moududul Haque
YR 2001
UL http://www.ajnr.org/content/22/2/311.abstract
AB Summary: We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA.