@article {Anzalone746, author = {Nicoletta Anzalone and Claudio Righi and Franco Simionato and Francesco Scomazzoni and Gilberto Pagani and Giliola Calori and Paolo Santino and Giuseppe Scotti}, title = {Three-dimensional Time-of-Flight MR Angiography in the Evaluation of Intracranial Aneurysms Treated with Guglielmi Detachable Coils}, volume = {21}, number = {4}, pages = {746--752}, year = {2000}, publisher = {American Journal of Neuroradiology}, abstract = {BACKGROUND AND PURPOSE: Intravascular treatment of intracranial aneurysms is a relatively new therapeutic technique and long-term controlled angiographic trials are needed to assess persistence of aneurysm occlusion. Our purpose was to evaluate the effectiveness of 3D time-of-flight (3D-TOF) MR angiography as a noninvasive screening tool in the follow-up of cerebral aneurysms treated with Guglielmi detachable coils (GDCs).METHODS: Forty-nine patients with 50 intracranial aneurysms previously treated with GDCs were studied with both DSA and 3D-TOF MR angiography. In 14 cases, a second follow-up examination was performed, for a total of 64 aneurysms evaluated. In 25 aneurysms, both pre- and postcontrast MR angiographic studies were obtained.RESULTS: In seven of 64 aneurysms, the MR angiographic studies were considered to be unreliable owing to the presence of artifacts that obscured part of the parent artery and did not allow an accurate evaluation of the aneurysm neck. These seven aneurysms, however, all were shown to be completely occluded at digital subtraction angiography (DSA). In the remaining 57 aneurysms, DSA revealed complete occlusion in 39 and the presence of residual patency in 18, whereas MR angiography showed complete occlusion in 38 and residual patency in 19. Enhanced MR angiography proved to be useful in evaluating residual patency in large and giant aneurysms and in better depicting the distal branch arteries.CONCLUSION: Although artifacts related to the presence of coils are evident on a considerable number of imaging studies, our findings indicate that MR angiography is useful in the evaluation of residual patency of cerebral aneurysms treated with GDCs and may eventually prove valuable in the follow-up of those cases in which a good initial correlation with DSA was demonstrated.}, issn = {0195-6108}, URL = {https://www.ajnr.org/content/21/4/746}, eprint = {https://www.ajnr.org/content/21/4/746.full.pdf}, journal = {American Journal of Neuroradiology} }