RT Journal Article
SR Electronic
T1 Iatrogenic Arterial Spasm Relieved by Intraarterial Mannitol Infusion
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 968
OP 970
VO 21
IS 5
A1 David Fortin
A1 Eva Osztie
A1 Edward A. Neuwelt
YR 2000
UL http://www.ajnr.org/content/21/5/968.abstract
AB Summary: Catheter placement for blood brain–barrier disruption and enhanced chemotherapy delivery can sometimes trigger arterial spasm of moderate-to-severe degree. A slow infusion of a small quantity of intraarterially administered mannitol (10 mL of 25% mannitol) was evaluated as a means to obtain a rapid resolution of catheter placement–induced spasm. We prospectively report 12 consecutive cases of blood brain–barrier disruption among patients who developed catheter placement–induced spasm that was treated by this means without side effects, resulting in rapid resolution of spasm.