PT  - JOURNAL ARTICLE
AU  - P. Gölitz
AU  - T. Struffert
AU  - F. Knossalla
AU  - M. Saake
AU  - S. Ott
AU  - O. Ganslandt
AU  - A. Doerfler
TI  - Angiographic CT with Intravenous Contrast Injection Compared with Conventional Rotational Angiography in the Diagnostic Work-Up of Cerebral Aneurysms
AID  - 10.3174/ajnr.A2883
DP  - 2012 May 01
TA  - American Journal of Neuroradiology
PG  - 982--987
VI  - 33
IP  - 5
4099  - http://www.ajnr.org/content/33/5/982.short
4100  - http://www.ajnr.org/content/33/5/982.full
SO  - Am. J. Neuroradiol.2012 May 01; 33
AB  - BACKGROUND AND PURPOSE: Noninvasive imaging of cerebral aneurysms is still considered inferior to conventional angiography. The purpose of this study was to evaluate the diagnostic accuracy of ivACT in the assessment of intracranial aneurysms compared with 3D-DSA. MATERIALS AND METHODS: We included 13 patients with 15 incidental unruptured saccular aneurysms scheduled for diagnostic angiographic work-up in our study. In each patient, we performed an ivACT and a conventional angiography including a 3D rotational run. During postprocessing, MPR images were generated for each technique. Maximal aneurysm diameter, neck diameter, aneurysm height, maximum width, bulge height, parent artery diameter, and angle between the parent artery and aneurysm apex were measured for each aneurysm. RESULTS: 3D-DSA and ivACT both provided images of high quality without artificial disturbances (ie, motion artifacts). Measurements of all parameters resulted in comparable values for both modalities with a strong correlation (P ≤ .001). CONCLUSIONS: ivACT is feasible for the noninvasive visualization of saccular cerebral aneurysms and may provide reliable diagnostic information for the assessment of aneurysm size and geometry comparable with conventional intra-arterial 3D rotational angiography. These preliminary results might be a first promising step to replacing conventional angiography in preinterventional aneurysm imaging. ACA A1anterior cerebral artery proximal to the origin of the anterior communicating arteryACTangiographic CTFPCTflat-detector CTivACTACT with intravenous contrast medium injectionMPRmultiplanar reformationMSCTmultisection CT3D-DSA3D rotational digital subtraction angiography