RT Journal Article
SR Electronic
T1 The New World Health Organization Classification of Central Nervous System Tumors: What Can the Neuroradiologist Really Say?
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 795
OP 802
DO 10.3174/ajnr.A2583
VO 33
IS 5
A1 A.G. Osborn
A1 K.L. Salzman
A1 M.M. Thurnher
A1 J.H. Rees
A1 M. Castillo
YR 2012
UL http://www.ajnr.org/content/33/5/795.abstract
AB SUMMARY: The WHO Classification of Tumors of the Central Nervous System has become the worldwide standard for classifying and grading brain neoplasms. The most recent edition (WHO 2007) introduced a number of significant changes that include both additions and redefinitions or clarifications of existing entities. Eight new neoplasms and 4 new variants were introduced. This article reviews these entities, summarizing both their histology and imaging appearance. Now with more than 3 years of clinical experience following publication of the newest revision, we also ask, “What can the neuroradiologist really say?” Are there imaging findings that could suggest the preoperative diagnosis of a new tumor entity or variant? aCPPatypical choriod plexus papillomaCNScentral nervous systemCPPchoriod plexus papillomaCPCachoriod plexus carcinomaDNETdysembryoplastic neuroepithelial tumorEVNCTextraventricular neurocytomaMBmedulloblastomaMBENmedulloblastoma with extensive nodularityPApilocytic astrocytomaPGNTpapillary glioneuronal tumorPMApilomyxoid astrocytomaPPTIDpineal parenchymal tumor of intermediate differentiationPTPRpapillary tumor of the pineal regionRGNTrosette-forming glioneuronal tumorSCOspindle cell oncocytomaT1C+post-contrast T1-weightedT1WIT1-weighted imagingT2WIT2-weighted imagingWHOWorld Health Organization