PT  - JOURNAL ARTICLE
AU  - H.M. Hussein
AU  - A.L. Georgiadis
AU  - A.I. Qureshi
TI  - Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures
AID  - 10.3174/ajnr.A2621
DP  - 2012 Aug 01
TA  - American Journal of Neuroradiology
PG  - 1211--1220
VI  - 33
IP  - 7
4099  - http://www.ajnr.org/content/33/7/1211.short
4100  - http://www.ajnr.org/content/33/7/1211.full
SO  - Am. J. Neuroradiol.2012 Aug 01; 33
AB  - SUMMARY: POC testing is defined as diagnostic testing at or near the site of patient care. Rapid measurement of the intensity of anticoagulation and, more recently, platelet inhibition allows dose titration of adjuvant medications such a heparin and antiplatelet agents during neuroendovascular procedures. However, knowledge among practicing physicians regarding the pathophysiologic basis of these measurements and variations in knowledge about the differences among devices is often limited. This review discusses the role of anticoagulation in endovascular procedures and the currently available POC tests for anticoagulation monitoring. ACTactivated clotting timeAnti-Xaquantitative chromogenic heparin assayaPTTactivated partial thromboplastin timeATantithrombinCIconfidence intervalGP IIb/IIIaglycoprotein IIb/IIIaHemonox-CTHemonox clotting timeHITheparin-induced thrombocytopeniaHMTHeparin Management TestIVintravenousLMWHlow-molecular-weight heparinMImyocardial infarctionORodds ratioPCIpercutaneous coronary interventionPOCpoint of careUFHunfractionated heparin