RT Journal Article
SR Electronic
T1 MR Angiography and Imaging for the Evaluation of Middle Cerebral Artery Atherosclerotic Disease
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1427
OP 1435
DO 10.3174/ajnr.A2697
VO 33
IS 8
A1 A.J. Degnan
A1 G. Gallagher
A1 Z. Teng
A1 J. Lu
A1 Q. Liu
A1 J.H. Gillard
YR 2012
UL http://www.ajnr.org/content/33/8/1427.abstract
AB SUMMARY: Intracranial atherosclerotic disease may constitute the most common cause of ischemic stroke worldwide; yet, in the developed world, imaging research has largely focused on extracranial atherosclerosis. Many studies in populations of Asian, African, and Hispanic descent demonstrate the preponderance of intracranial stenosis compared with carotid stenosis. This review examines the clinical presentations of MCA atherosclerosis and stenosis and the use of noninvasive MR imaging in the assessment of intracranial vasculature. MRA is a well-validated technique that offers great advantage over traditional angiography. Advances in high-resolution MR imaging of MCA stenosis have the potential to yield excellent visualization of plaque. Future developments in high-resolution MR imaging to depict intracranial atherosclerosis are explored in this review; these advances will guide endovascular therapy and the comparison of novel interventions. TOFtime-of-flightTCDtranscranial Doppler