PT  - JOURNAL ARTICLE
AU  - G.Q. Hou
AU  - J.C. Sun
AU  - X.J. Zhang
AU  - B.X. Shen
AU  - X.J. Zhu
AU  - L. Liang
AU  - X.L. Zhang
TI  - MR Imaging Findings of the Intraspinal Meningeal Melanocytoma: Correlation with Histopathologic Findings
AID  - 10.3174/ajnr.A2987
DP  - 2012 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1525--1529
VI  - 33
IP  - 8
4099  - http://www.ajnr.org/content/33/8/1525.short
4100  - http://www.ajnr.org/content/33/8/1525.full
SO  - Am. J. Neuroradiol.2012 Sep 01; 33
AB  - SUMMARY: Our aim was to better understand and improve the accuracy of the preoperative diagnosis of intraspinal MM by a combined analysis of MR imaging and pathologic findings. All 5 patients had undergone unenhanced and contrast-enhanced MR imaging examinations. All tumor samples had immunohistochemical reactions to HMB-45, vimentin, S-100, EMA, and Leu-7 antibodies. All 5 cases were located in the intradural extramedullary compartment. Two cases had multifocal lesions, and 3 cases were solitary. Two cases showed homogeneously strong enhancement, and 3 cases showed moderate enhancement on contrast-enhanced T1WI. The tumor cells had positive reactions to HMB-45, vimentin, and S-100 antibodies. MR imaging plays an important role in the detection and diagnosis of intraspinal MM. Final diagnosis should be based on histopathology and IHC examinations. EMAepithelial membrane antigenHMB-45human melanoma black-45IHCimmunohistochemistryMMmeningeal melanocytoma