RT Journal Article
SR Electronic
T1 Platelet-Function Testing in Patients Undergoing Neurovascular Procedures: Caught between a Rock and a Hard Place
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 730
OP 734
DO 10.3174/ajnr.A3440
VO 34
IS 4
A1 J. Comin
A1 D.F. Kallmes
YR 2013
UL http://www.ajnr.org/content/34/4/730.abstract
AB SUMMARY: In the context of neurointerventional procedures, clopidogrel hyper-responsiveness has been associated with hemorrhage; on the other hand, clopidogrel resistance has been associated with thromboembolism. This might seem to make a compelling argument in favor of routine platelet testing. Our reading of the literature leads us to conclude that routine platelet testing in neurointerventional procedures is not, unfortunately, ready for prime time. CRESTClopidogrel Effect on Platelet Reactivity in Patients with Stent ThrombosisGRAVITASGauging Responsiveness with a VerifyNow AssayOASIS-7Optimal Antiplatelet Strategy for InterventionsPCIpercutaneous coronary interventionPOPULARPoint-of-Care Platelet Function Assays Predict Clinical Outcomes in Clopidogrel pre-treated patients undergoing elective PCITRIGGER-PCITesting Platelet Reactivity in Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternate Therapy with Prasugrel.