RT Journal Article SR Electronic T1 Digital Subtraction Cerebral Angiography by Intraarterial Injection: Comparison with Conventional Angiography JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 593 OP 599 VO 3 IS 6 A1 Michael Brant-Zawadzki A1 Robert Gould A1 David Norman A1 Thomas H. Newton A1 Barton Lane YR 1982 UL http://www.ajnr.org/content/3/6/593.abstract AB For 4 months, a prototype digital subtraction system was used to obtain images of the cerebral vasculature after intraarterial contrast injections. In 12 instances, the intraarterial injections were recorded with both a digital subtraction unit and conventional direct magnification film-screen system. The digital subtraction and conventional film subtraction images were compared and graded for quality and information content by three skilled observers. In addition, quantitative measurements of contrast-detail performance and spatial resolution were obtained on both the digital system and the screen-film imaging chain. In a clinical setting, both the digital subtraction and conventional film-screen systems provided similar quality images and angiographic information. Contrast-detail curves demonstrated that digital subtraction angiography outperformed conventional film technique for low-contrast objects. Digital subtraction angiography also reduced the time required to obtain the angiogram, markedly reduced film cost, and lowered the contrast agent burden.