PT - JOURNAL ARTICLE AU - Y. Gunduz AU - R. Akdemir AU - L.T. Ayhan AU - N. Keser TI - Can Doppler Flow Parameters of Carotid Stenosis Predict the Occurrence of New Ischemic Brain Lesions Detected by Diffusion-Weighted MR Imaging after Filter-Protected Internal Carotid Artery Stenting? AID - 10.3174/ajnr.A3904 DP - 2014 Apr 01 TA - American Journal of Neuroradiology PG - 760--765 VI - 35 IP - 4 4099 - http://www.ajnr.org/content/35/4/760.short 4100 - http://www.ajnr.org/content/35/4/760.full SO - Am. J. Neuroradiol.2014 Apr 01; 35 AB - BACKGROUND AND PURPOSE: Carotid angioplasty and stent placement are increasingly being used for the treatment of symptomatic and asymptomatic carotid artery disease. Carotid angioplasty and stent placement carry an inherent risk of distal cerebral embolization, precipitating new brain ischemic lesions and neurologic symptoms. Our purpose was to evaluate the frequency of new ischemic lesions found on diffusion-weighted imaging after protected carotid angioplasty and stent placement and to determine the association of new lesions with ICA Doppler flow parameters. MATERIALS AND METHODS: Fifty-two patients (mean age, 68 ± 11 years) with 50%–69% (n = 20, group 1) and ≥70% (n = 32, group 2) internal carotid artery stenosis underwent carotid angioplasty and stent placement with distal filter protection. DWI was performed before and 48 hours after carotid angioplasty and stent placement. RESULTS: Thirty-three (63.4%) patients showed new lesions. The average number of new postprocedural lesions was 3.4 per patient. Most of the postprocedural lesions were <5 mm (range, 3–23 mm), cortical and corticosubcortical, and clinically silent. Group 2 had a significantly higher number of new lesions compared with group 1 (P < .001). A significant relationship was found between ICA Doppler flow parameters and the appearance of new lesions. CONCLUSIONS: The appearance of new ischemic lesions was significantly related to the Doppler flow parameters, particularly peak systolic velocity. CAScarotid artery stentingCCAcommon carotid arteryEDVend-diastolic velocityPSVpeak systolic velocity