PT - JOURNAL ARTICLE AU - G. Suffredini AU - J.E. East AU - L.M. Levy TI - New Applications of Nanotechnology for Neuroimaging AID - 10.3174/ajnr.A3543 DP - 2014 Jul 01 TA - American Journal of Neuroradiology PG - 1246--1253 VI - 35 IP - 7 4099 - http://www.ajnr.org/content/35/7/1246.short 4100 - http://www.ajnr.org/content/35/7/1246.full SO - Am. J. Neuroradiol.2014 Jul 01; 35 AB - SUMMARY: Advances in nanotechnology have the potential to dramatically enhance the detection of neurologic diseases with targeted contrast agents and to facilitate the delivery of focused therapies to the central nervous system. We present the physicochemical rationale for their use, applications in animal models, and ongoing clinical trials using these approaches. We highlight advances in the use of nanoparticles applied to brain tumor imaging, tumor angiogenesis, neurodegeneration, grafted stem cells, and neuroprogenitor cells. amyloid betaAβNOnitric oxideNOSnitric oxide synthasePBCApoly(n-butyl cyanoacrylate)QDotsquantum dotsSPIOsuperparamagnetic iron oxide