RT Journal Article SR Electronic T1 Imaging and Treatment of Patients with Acute Stroke: An Evidence-Based Review JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1045 OP 1051 DO 10.3174/ajnr.A3518 VO 35 IS 6 A1 P.C. Sanelli A1 J.B. Sykes A1 A.L. Ford A1 J.-M. Lee A1 K.D. Vo A1 D.K. Hallam YR 2014 UL http://www.ajnr.org/content/35/6/1045.abstract AB SUMMARY: Evidence-based medicine has emerged as a valuable tool to guide clinical decision-making, by summarizing the best possible evidence for both diagnostic and treatment strategies. Imaging plays a critical role in the evaluation and treatment of patients with acute ischemic stroke, especially those who are being considered for thrombolytic or endovascular therapy. Time from stroke-symptom onset to treatment is a strong predictor of long-term functional outcome after stroke. Therefore, imaging and treatment decisions must occur rapidly in this setting, while minimizing unnecessary delays in treatment. The aim of this review was to summarize the best available evidence for the diagnostic and therapeutic management of patients with acute ischemic stroke. DPMdiffusion-perfusion mismatchIAintra-arterialICHintracranial hemorrhager-proUKrecombinant prourokinaseTIMIThrombolysis in Myocardial Infarction