RT Journal Article
SR Electronic
T1 Association between Resting-State Coactivation in the Parieto-Frontal Network and Intelligence during Late Childhood and Adolescence
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1150
OP 1156
DO 10.3174/ajnr.A3850
VO 35
IS 6
A1 C. Li
A1 L. Tian
YR 2014
UL http://www.ajnr.org/content/35/6/1150.abstract
AB BACKGROUND AND PURPOSE: A number of studies have associated the adult intelligence quotient with the structure and function of the bilateral parieto-frontal networks, whereas the relationship between intelligence quotient and parieto-frontal network function has been found to be relatively weak in early childhood. Because both human intelligence and brain function undergo protracted development into adulthood, the purpose of the present study was to provide a better understanding of the development of the parieto-frontal network–intelligence quotient relationship. MATERIALS AND METHODS: We performed independent component analysis of resting-state fMRI data of 84 children and 50 adolescents separately and then correlated full-scale intelligence quotient with the spatial maps of the bilateral parieto-frontal networks of each group. RESULTS: In children, significant positive spatial-map versus intelligence quotient correlations were detected in the right angular gyrus and inferior frontal gyrus in the right parieto-frontal network, and no significant correlation was observed in the left parieto-frontal network. In adolescents, significant positive correlation was detected in the left inferior frontal gyrus in the left parieto-frontal network, and the correlations in the frontal pole in the 2 parieto-frontal networks were only marginally significant. CONCLUSIONS: The present findings not only support the critical role of the parieto-frontal networks for intelligence but indicate that the relationship between intelligence quotient and the parieto-frontal network in the right hemisphere has been well established in late childhood, and that the relationship in the left hemisphere was also established in adolescence. IQintelligence quotientFSIQfull-scale intelligence quotientPFNparieto-frontal networkRS-fMRIresting-state fMRITC-GICAtemporal-concatenation group independent component analysisR.PFNright PFNL.PFNleft PFNIFGinferior frontal gyrus