RT Journal Article SR Electronic T1 WEB Intrasaccular Flow Disruptor—Prospective, Multicenter Experience in 83 Patients with 85 Aneurysms JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 2106 OP 2111 DO 10.3174/ajnr.A4028 VO 35 IS 11 A1 C. Papagiannaki A1 L. Spelle A1 A.-C. Januel A1 A. Benaissa A1 J.-Y. Gauvrit A1 V. Costalat A1 H. Desal A1 F. Turjman A1 S. Velasco A1 X. Barreau A1 P. Courtheoux A1 C. Cognard A1 D. Herbreteau A1 J. Moret A1 L. Pierot YR 2014 UL http://www.ajnr.org/content/35/11/2106.abstract AB BACKGROUND AND PURPOSE: The safety and efficacy of WEB flow disruption have been analyzed in small, retrospective series. The object of this study was to evaluate the safety and efficacy of WEB flow disruption in a large, multicenter, prospectively collected population. MATERIALS AND METHODS: Data from all patients treated with the WEB-DL device between June 2011 and October 2013 in 11 French neurointerventional centers were prospectively collected and retrospectively analyzed. Complications occurring during and after treatment were analyzed as well as morbidity and mortality at 1 month. Aneurysm occlusion status at the last follow-up was analyzed. RESULTS: Eighty-three patients with 85 aneurysms were included in this series. Technical success was achieved in 77 patients with 79 aneurysms (92.9%). Periprocedural complications were observed in 9 patients (10.8%), leading to permanent neurologic deficits in 3 (3.9%). Morbidity and mortality at 1 month were 1.3% and 0.0%, respectively. Angiographic follow-up was performed for 65/79 aneurysms (82.3%) 3–24 months after treatment (mean, 5.3 months). Complete aneurysm occlusion was observed in 37/65 aneurysms (56.9%); neck remnant, in 23/65 (35.4%); and aneurysm remnant, in 5/65 (7.7%). CONCLUSIONS: In this large prospective series of patients, WEB flow disruption was a safe and efficient technique. AcomAanterior communicating arteryATENAAnalysis of Treatment by Endovascular Approach of Nonruptured AneurysmsCLARITYClinical and Anatomic Results in the Treatment of Ruptured Intracranial AneurysmsDLDual LayerWEBWoven Endoluminal Bridge