RT Journal Article
SR Electronic
T1 Dynamic Angiography and Perfusion Imaging Using Flat Detector CT in the Angiography Suite: A Pilot Study in Patients with Acute Middle Cerebral Artery Occlusions
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1964
OP 1970
DO 10.3174/ajnr.A4383
VO 36
IS 10
A1 T. Struffert
A1 Y. Deuerling-Zheng
A1 S. Kloska
A1 T. Engelhorn
A1 S. Lang
A1 A. Mennecke
A1 M. Manhart
A1 C.M. Strother
A1 S. Schwab
A1 A. Doerfler
YR 2015
UL http://www.ajnr.org/content/36/10/1964.abstract
AB BACKGROUND AND PURPOSE: Perfusion and angiographic imaging using intravenous contrast application to evaluate stroke patients is now technically feasible by flat detector CT performed by the angiographic system. The aim of this pilot study was to show the feasibility and qualitative comparability of a novel flat detector CT dynamic perfusion and angiographic imaging protocol in comparison with a multimodal stroke MR imaging protocol.MATERIALS AND METHODS: In 12 patients with acute stroke, MR imaging and the novel flat detector CT protocol were performed before endovascular treatment. Perfusion parameter maps (MTT, TTP, CBV, CBF) and MIP/volume-rendering technique images obtained by using both modalities (MR imaging and flat detector CT) were compared.RESULTS: Comparison of MIP/volume-rendering technique images demonstrated equivalent visibility of the occlusion site. Qualitative comparison of perfusion parameter maps by using ASPECTS revealed high Pearson correlation coefficients for parameters CBF, MTT, and TTP (0.95–0.98), while for CBV, the coefficient was lower (0.49).CONCLUSIONS: We have shown the feasibility of a novel dynamic flat detector CT perfusion and angiographic protocol for the diagnosis and triage of patients with acute ischemic stroke. In a qualitative comparison, the parameter maps and MIP/volume-rendering technique images compared well with MR imaging. In our opinion, this flat detector CT application may substitute for multisection CT imaging in selected patients with acute stroke so that in the future, patients with acute stroke may be directly referred to the angiography suite, thereby avoiding transportation and saving time.FD-CTflat detector CTFD-CTAflat detector CT dynamic perfusion and angiographic imagingFD-CTPflat detector CT dynamic perfusionMRPMR perfusion imagingMS-CTmultisection CT