PT  - JOURNAL ARTICLE
AU  - H Rumpel
AU  - B Ferrini
AU  - E Martin
TI  - Lasting cytotoxic edema as an indicator of irreversible brain damage: a case of neonatal stroke.
DP  - 1998 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1636--1638
VI  - 19
IP  - 9
4099  - http://www.ajnr.org/content/19/9/1636.short
4100  - http://www.ajnr.org/content/19/9/1636.full
SO  - Am. J. Neuroradiol.1998 Oct 01; 19
AB  - We describe a case of neonatal stroke in the territory of the left middle cerebral artery. Although the ischemic lesion appeared rather homogeneously hyperintense on T2-weighted MR images, corresponding diffusion-weighted images clearly delineated two separate zones of different cellular swelling and, thus, different prognoses. Lasting cytotoxic edema heralded infarction. We believe that the different rates of disintegration of neurons and glial cells may have caused the change from intracellular to interstitial volume fraction during the evolution of edema.