RT Journal Article
SR Electronic
T1 Brain Fluorine-18 Fluorodeoxyglucose Imaging with Dual-Head Coincidence Gamma Camera:Comparison with Dedicated Ring-Detector PositronEmission Tomography
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 99
OP 104
VO 21
IS 1
A1 Fukuchi, Kazuki
A1 Hayashida, Kohei
A1 Moriwaki, Hiroshi
A1 Fukushima, Kazuhito
A1 Kume, Norihiko
A1 Katafuchi, Tetsuro
A1 Sago, Masayoshi
A1 Takamiya, Makoto
A1 Ishida, Yoshio
YR 2000
UL http://www.ajnr.org/content/21/1/99.abstract
AB BACKGROUND AND PURPOSE: Dual-head coincidence gamma camera (DHC) imaging has been proposed as an alternative to dedicated ring-detector positron emission tomography (dr-PET) for clinical fluorodeoxyglucose (FDG) studies. The purpose of this investigation was to assess the quality of DHC images in FDG studies of the human brain.METHODS: Seven healthy volunteers and 12 patients with various cerebral disorders underwent consecutive brain dr-PET and DHC with FDG. All sets of images were compared semiquantitatively using regions of interest.RESULTS: Cortical count ratios to the cerebellum on DHC and dr-PET images did not differ significantly among the volunteers, except in the superior frontal cortex and thalamus. In all studies including those of cerebral disorders, the mean cortical-to-cerebellar ratios of DHC and dr-PET images correlated closely.CONCLUSION: FDG imaging with DHC delineated the metabolic distribution of glucose in the brain as well as dr-PET did, except in the superior frontal cortex and thalamus. Therefore, DHC may be a dedicated cost-effective means of detecting metabolic abnormalities in the brain.