@article {Choi834, author = {Choong-Gon Choi and Han Wook Yoo}, title = {Localized Proton MR Spectroscopy in Infants with Urea Cycle Defect}, volume = {22}, number = {5}, pages = {834--837}, year = {2001}, publisher = {American Journal of Neuroradiology}, abstract = {Summary: Urea cycle defect is an inborn error of ammonium metabolism caused by a deficient activity of the enzymes involved in urea synthesis. Localized short-TE proton MR spectroscopy, performed in two infants who had citrullinemia and ornithine transcarbamylase deficiency, respectively, showed a prominent increase of glutamine/glutamate and lipid/lactate complex in both cases. N-acetylaspartate, total creatine, and myo-inositol were decreased in the infant with citrullinemia. Proton MR spectroscopy provided useful information for the diagnosis and understanding of the pathophysiology of urea cycle enzyme defect.}, issn = {0195-6108}, URL = {https://www.ajnr.org/content/22/5/834}, eprint = {https://www.ajnr.org/content/22/5/834.full.pdf}, journal = {American Journal of Neuroradiology} }