RT Journal Article SR Electronic T1 Regional Cerebral Glucose Metabolism and Blood Flow in a Patient with Marchiafava-Bignami Disease JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1249 OP 1251 VO 20 IS 7 A1 Ishii, Kazunari A1 Ikejiri, Yoshitaka A1 Sasaki, Masahiro A1 Kitagaki, Hajime A1 Mori, Etsuro YR 1999 UL http://www.ajnr.org/content/20/7/1249.abstract AB Summary: We report functional neuroimaging studies of a 54-year-old man with Marchiafava-Bignami disease (MBD). Glucose metabolic images obtained by [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography showed diffusely reduced whole brain metabolism and strongly decreased metabolism in the frontal and parietal lobes, orbital gyrus, and thalamus. Cerebral perfusion images showed a similarly decreased radioactivity pattern as the metabolic images. Functional neuroimages would be useful for understanding the pathophysiologic processes of MBD.