RT Journal Article SR Electronic T1 Optimization of Gray/White Matter Contrast with Fast Inversion Recovery for Myelin Suppression: A Comparison of Fast Spin-Echo and Echo-Planar MR Imaging Sequences JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1653 OP 1657 VO 20 IS 9 A1 Leo J. Wolansky A1 Steven G. Finden A1 Janet Chen A1 Rafik Hanna A1 Andrei I. Holodny A1 Imtiaz Ahmad A1 Wen Ching Liu A1 Sohail Contractor YR 1999 UL http://www.ajnr.org/content/20/9/1653.abstract AB Summary: We compared two MR imaging sequences, fast inversion recovery for myelin suppression (FIRMS) and echo-planar FIRMS (EP-FIRMS), for depicting gray/white matter contrast. In 18 patients, the frequency bandwidth (BW) was optimized for each sequence; in nine patients, the BW was held constant. In the BW-optimized group, the mean contrast-to-noise ratio (C/N) was three times higher with the FIRMS sequence. In the BW-constant group, the mean C/N was 27% higher with the EP-FIRMS sequence; however, geometric distortion degraded the EP-FIRMS images excessively. For optimal gray/white contrast, FIRMS appears to be the superior pulse sequence.