TY - JOUR T1 - Coexistent Holoprosencephaly and Chiari II Malformation JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1678 LP - 1681 VL - 20 IS - 9 AU - Nancy Rollins AU - Jeanne Joglar AU - Jeffery Perlman Y1 - 1999/10/01 UR - http://www.ajnr.org/content/20/9/1678.abstract N2 - Summary: Chiari II malformations and holoprosencephaly have been considered to be brain malformations that differ with respect to teratogenic insult, embryologic mechanism, and morphology. We herein describe coexistent Chiari II malformation and holoprosencephaly that occurred in a viable infant. A review of the literature regarding Chiari II malformations and holoprosencephaly suggests that a disturbance to the mesenchyme in early embryologic life may be the cause of both malformations. ER -