TY - JOUR T1 - Magnetization Transfer Ratio Is Unable to Lateralize Epileptic Foci in Patients with Temporal Lobe Epilepsy JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1853 LP - 1856 VL - 21 IS - 10 AU - Li Min Li AU - Sridar Narayanan AU - Gilbert Bruce Pike AU - Frederick Andermann AU - François Dubeau AU - Douglas L. Arnold Y1 - 2000/11/01 UR - http://www.ajnr.org/content/21/10/1853.abstract N2 - BACKGROUND AND PURPOSE: A preliminary report suggested that magnetization transfer ratio (MTR) was useful to lateralize epileptic foci in patients with refractory temporal lobe epilepsy (TLE). We attempted to confirm this finding in a larger group by investigating the relationship between MTR of mesial temporal structures and seizure lateralization in patients with refractory TLE.METHODS: We compared the MTR of amygdalae and hippocampi of 10 patients with unilateral TLE to values obtained from 10 healthy control participants.RESULTS: Three of 10 patients with TLE had MTR values that were 2 SD below the normal mean; the MTR abnormality was concordant with electroclinical lateralization in only one of the three.CONCLUSION: We conclude that MTR measurements of amygdalae and hippocampi are not useful for lateralization of TLE. ER -