RT Journal Article
SR Electronic
T1 Cerebral Cortical and White Matter Lesions in Chronic Hepatic Encephalopathy: MR-Pathologic Correlations
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 347
OP 351
VO 26
IS 2
A1 Matsusue, Eiji
A1 Kinoshita, Toshibumi
A1 Ohama, Eisaku
A1 Ogawa, Toshihide
YR 2005
UL http://www.ajnr.org/content/26/2/347.abstract
AB Summary: We correlated MR images with histologic findings in two autopsy-proven cases of chronic hepatic encephalopathy. Cortical hyperintensities on T2-weighted images histologically revealed pseudolaminar spongy degeneration in the deep layers of the cerebral cortices and hyperintensities in the cerebral white matters showed tissue rarefaction associated with loss of myelin and axons but without reactive astrocytosis. Both lesions were considered to be caused by chronic hepatic encephalopathy.