RT Journal Article
SR Electronic
T1 MR Imaging-Guided Interstitial Photodynamic Laser Therapy for Advanced Head and Neck Tumors
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1193
OP 1200
VO 26
IS 5
A1 H. Rolf Jäger
A1 Magali N. Taylor
A1 Tamer Theodossy
A1 Colin Hopper
YR 2005
UL http://www.ajnr.org/content/26/5/1193.abstract
AB Summary: Photodynamic therapy (PDT) is a site-specific tumor treatment involving the administration of a photosensitizer activated by the local application of light. In interstitial PDT (IPDT), multiple laser fibers are inserted into the depth of the tumor. Image guidance is essential for accurate, safe, and uniform light delivery. We report a novel technique of IPDT for advanced head and neck tumors involving an open interventional MR system. Initial results are encouraging, with minimal procedural morbidity, successful palliation of symptoms, and prolongation of expected survival time.