TY - JOUR T1 - Secondary Supratentorial Primitive Neuroectodermal Tumor following Irradiation in a Patient with Low-Grade Astrocytoma JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 160 LP - 162 VL - 26 IS - 1 AU - Allan Y. Chen AU - Haidy Lee AU - Jonathan Hartman AU - Claudia Greco AU - Janice K. Ryu AU - Robert O’Donnell AU - James Boggan Y1 - 2005/01/01 UR - http://www.ajnr.org/content/26/1/160.abstract N2 - Summary: We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, PNET needs to be included in the differential diagnoses for previously irradiated patients, who develop recurrent brain tumors in the presence of uncharacteristic imaging features. ER -