RT Journal Article SR Electronic T1 Effect of Thin-Section Diffusion-Weighted MR Imaging on Stroke Diagnosis JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 560 OP 565 VO 26 IS 3 A1 Hisao Nakamura A1 Kei Yamada A1 Osamu Kizu A1 Hirotoshi Ito A1 Sachiko Yuen A1 Takaaki Ito A1 Kenji Yoshikawa A1 Kensuke Shiga A1 Masanori Nakagawa A1 Tsunehiko Nishimura YR 2005 UL http://www.ajnr.org/content/26/3/560.abstract AB BACKGROUND AND PURPOSE: Diffusion-weighted (DW) imaging has limited spatial resolution, especially in the z direction. We decreased the section thickness of DW imaging to 3 mm to determine if this change improves the depiction of small infarcts and if it affects stroke diagnosis.METHODS: We studied conventional (5-mm section thickness, 1-mm intersection gap) and thin-section (3-mm section thickness, no intersection gap) DW imaging data in 49 patients with symptoms of acute cerebral ischemia. Two radiologists who were not aware of the clinical findings reviewed all images and diagnosed the stroke subtype according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) method. Accuracies of stroke diagnosis with an experienced neuroradiologist and with a second-year radiology resident were compared. To quantify lesion conspicuity, contrast-to-noise ratios (CNRs) were measured. The CNR of thin-section DW imaging was then divided by the CNR of conventional DW imaging to yield the relative CNR (rCNR).RESULTS: The experienced neuroradiologist made the correct final diagnoses in 78% of cases with conventional DW imaging, improving to 100% with thin-section DW imaging. The resident made the correct diagnoses in 71% of cases with conventional DW imaging, improving to 94% with thin-section DW imaging. Lesion conspicuity was improved on thin-section DW imaging (rCNR = 1.47 ± 0.63), especially for supratentorial lesions (rCNR = 1.51 ± 0.63).CONCLUSION: Compared with conventional DW imaging, thin-section DW imaging permitted better lesion conspicuity and more precise stroke diagnosis.