TY - JOUR T1 - Carotid Stent Delivery in an XMR Suite: Immediate Assessment of the Physiologic Impact of Extracranial Revascularization JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 531 LP - 537 VL - 26 IS - 3 AU - Alastair J. Martin AU - David A. Saloner AU - Timothy P. L. Roberts AU - Heidi Roberts AU - Oliver M. Weber AU - William Dillon AU - Sean Cullen AU - Van Halbach AU - Christopher F. Dowd AU - Randall T. Higashida Y1 - 2005/03/01 UR - http://www.ajnr.org/content/26/3/531.abstract N2 - BACKGROUND AND PURPOSE: Patients undergoing stent placement as treatment for severe stenosis of the internal carotid artery (ICA) were assessed with MR imaging in a combined MR–radiographic (XMR) angiography suite. MR imaging was performed before and immediately following conventional radiography–guided stent placement. Changes in MR imaging measurable properties, including flow and perfusion, resulting from stent placement were evaluated.PATIENTS AND TECHNIQUES: MR imaging analysis was performed for 12 patients with >70% stenosis of the ICA before and after conventional radiography–guided deployment of a carotid stent. MR imaging acquisitions included angiography, quantitative flow analysis, perfusion, diffusion, and turbo–fluid-attenuated inversion recovery (FLAIR). These acquisitions were all performed immediately before and following stent placement by using conventional techniques.RESULTS: MR angiography proved sufficient for identifying the target lesion and permitting targeted flow analysis. MR flow analysis demonstrated a marked increase in flow in the treated carotid artery (+2.2 ± 1.2 mL/s) and little change in other extracranial arteries. MR perfusion imaging showed no significant differences in relative cerebral blood volume between hemispheres before or after treatment, but there was a modest decrease in mean transit time and time to peak evident in the treated hemisphere after stent placement. Diffusion imaging did not demonstrate any ischemic foci resulting from carotid stent treatment. Hyperintensity of the CSF was noted on turbo-FLAIR acquisitions in the ipsilateral hemisphere following stent placement in 75% of patients.CONCLUSION: MR imaging reliably reflects the state of the carotid artery and provides a means of monitoring and quantifying the effects of revascularization. ER -