PT  - JOURNAL ARTICLE
AU  - Bernd L. Schmitz
AU  - Georg Grön
AU  - Florian Brausewetter
AU  - Martin H.K. Hoffmann
AU  - Andrik J. Aschoff
TI  - Enhancing Gray-to-White Matter Contrast in 3T T1 Spin-Echo Brain Scans by Optimizing Flip Angle
DP  - 2005 Sep 01
TA  - American Journal of Neuroradiology
PG  - 2000--2004
VI  - 26
IP  - 8
4099  - http://www.ajnr.org/content/26/8/2000.short
4100  - http://www.ajnr.org/content/26/8/2000.full
SO  - Am. J. Neuroradiol.2005 Sep 01; 26
AB  - BACKGROUND AND PURPOSE: Compared with MR imaging at 1.5T T1-weighted spin-echo imaging at 3T shows up with reduced gray-to-white matter contrast. The purpose of the present study was to show the effects of alterations of different flip angles as an easily accessible parameter to increase gray-to-white matter contrast.METHODS: Spin-echo T1 sequences of 6 healthy volunteers were acquired in a 3T head scanner with 5 different flip angles. Observer-independent contrast-to-noise ratios for gray versus white matter from different flip angles, as well as subjective ratings of image quality from 2 blinded neuroradiologists, were compared statistically.RESULTS: Gray-to-white matter contrast increased significantly with decreasing flip angle. No artifacts were introduced by decreasing flip angles, and T1 contrast characteristics were robust and stable at lowered flip angles. Also, specific absorption ratios significantly decreased with decreasing flip angles.CONCLUSION: Using a flip angle of 50° significantly increases gray-to-white matter contrast in T1 spin-echo brain scans at 3T B0 field strength.