RT Journal Article
SR Electronic
T1 Serial MR Imaging Findings of Acute Hemorrhagic Leukoencephalitis: A Case Report
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1996
OP 1999
VO 26
IS 8
A1 Ho Yun Lee
A1 Kee-Hyun Chang
A1 Ji Hoon Kim
A1 Dong Gyu Na
A1 Bae Ju Kwon
A1 Kwang-Woo Lee
A1 Sung Hye Park
YR 2005
UL http://www.ajnr.org/content/26/8/1996.abstract
AB Summary: We report a patient with acute hemorrhagic leukoencephalitis with a focus on serial MR imaging findings. Initial MR imaging of a 42-year-old woman revealed a 2.5-cm focal nonhemorrhagic lesion in the left thalamus and internal capsule. Twenty-four days later, fever and altered consciousness developed, and MR imaging showed huge masslike lesions in both frontal lobes, mainly involving the white matter and the genu of the corpus callosum, with massive edematous swelling that contained multifocal small hemorrhages. Most lesions showed high apparent diffusion coefficient value with peripheral small areas of low apparent diffusion coefficient. On follow-up MR imaging obtained 49 days after initial MR imaging, the lesions progressed with increase in extent and development of rim-enhancing necrosis, despite steroid therapy. Following stereotactic biopsy and subsequent high-dose steroid treatment, the patient recovered with some neurologic sequelae. MR imaging obtained at 72 and 126 days revealed residual necrosis and cerebromalacia in the both frontal lobes.