TY - JOUR T1 - Prominent Perivenular Spaces in Multiple Sclerosis as a Sign of Perivascular Inflammation in Primary Demyelination JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 2316 LP - 2319 VL - 26 IS - 9 AU - Yulin Ge AU - Meng Law AU - Joseph Herbert AU - Robert I. Grossman Y1 - 2005/10/01 UR - http://www.ajnr.org/content/26/9/2316.abstract N2 - Summary: In this study, we describe prominent perivenular spaces as a sign that is seen on high-resolution (512 × 512) transverse T2-weighted MR images in patients with multiple sclerosis. The observed widening of perivenular space is depicted as a stringlike hyperintensity projecting radially and aligned with multiple sclerosis lesions (usually small), following the course and configuration of deep venular structures. This widening may be an important sign in differentiating primary (ie, in multiple sclerosis) from secondary causes of demyelination. ER -