RT Journal Article
SR Electronic
T1 Brain iron in patients with Parkinson disease: MR visualization using gradient modification.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 237
OP 240
VO 9
IS 2
A1 J F Norfray
A1 N L Chiaradonna
A1 W J Heiser
A1 S H Song
A1 B V Manyam
A1 A B Devleschoward
A1 L M Eastwood
YR 1988
UL http://www.ajnr.org/content/9/2/237.abstract
AB In patients with Parkinson disease, improved visualization of brain iron on a mid-field-strength magnet can be obtained with T2-weighted images and elimination of phase-encoding artifacts. A long echo delay time accentuates the loss of signal from brain iron. However, the long pulse sequence creates phase-encoding artifacts from CSF pulsations at the level of the basal ganglia. These artifacts are eliminated and resolving power increased with additional pulsing in the slice-selective and read gradients. Elimination of motion artifacts enhances visualization of brain iron in three ways: (1) extrapyramidal nuclei containing iron have better definition, (2) abnormalities are better identified, and (3) pseudolesions disappear. Our findings suggest there is significant improvement in the resolving power of brain iron on MR scans made with a mid-field-strength scanner when gradient modification is used.