PT - JOURNAL ARTICLE AU - O P Eldevik AU - P Nakstad AU - B E Kendall AU - T Hindmarsh TI - Iohexol in lumbar myelography: preliminary results from an open, noncomparative multicenter clinical study. DP - 1983 May 01 TA - American Journal of Neuroradiology PG - 299--301 VI - 4 IP - 3 4099 - http://www.ajnr.org/content/4/3/299.short 4100 - http://www.ajnr.org/content/4/3/299.full SO - Am. J. Neuroradiol.1983 May 01; 4 AB - This is a preliminary report of the first clinical trials using iohexol as a contrast agent in lumbar myelography. The study was noncomparative and involved 82 adult patients in four centers. Iohexol doses of 10-15 ml (180 mg I/ml) were administered and clinical and laboratory tests were performed before and at intervals during 48 hr after myelography. Side effects were noted in 29 (35%) of 82 patients. Spinal repuncture 6 or 24 hr after myelography was performed in 51 patients. No significant increases in cerebrospinal fluid parameters were seen. No seizures or spikes on electroencephalography were seen.