RT Journal Article
SR Electronic
T1 In vivo NMR imaging of tissue sodium in the intact cat before and after acute cerebral stroke.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 245
OP 249
VO 4
IS 3
A1 S K Hilal
A1 A A Maudsley
A1 H E Simon
A1 W H Perman
A1 J Bonn
A1 M E Mawad
A1 A J Silver
A1 S R Ganti
A1 P Sane
A1 I C Chien
YR 1983
UL http://www.ajnr.org/content/4/3/245.abstract
AB The first in vivo nuclear magnetic resonance (NMR) images of tissue sodium in the intact animal are presented. The distribution of sodium in the normal cat's head is described. An experimental stroke was surgically induced. Sodium NMR imaging showed a pronounced focal increase in cerebral sodium concentration 9 hr after ligation of the middle cerebral artery. The method appears to be very sensitive for early detection of infarction. The measured increase in the regional sodium NMR signal probably reflects both a true increase in concentration of brain sodium and an increased NMR visibility of the sodium nucleus in the region of the infarction.