TY - JOUR T1 - PET studies of glucose metabolism in patients with schizophrenia. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 550 LP - 552 VL - 4 IS - 3 AU - L Widen AU - G Blomqvist AU - T Greitz AU - J E Litton AU - M Bergström AU - E Ehrin AU - K Ericson AU - L Eriksson AU - D H Ingvar AU - L Johansson AU - J L Nilsson AU - S Stone-Elander AU - G Sedvall AU - F Wiesel AU - G Wiik Y1 - 1983/05/01 UR - http://www.ajnr.org/content/4/3/550.abstract N2 - The hypothesis of abnormal patterns of metabolism in schizophrenia was examined in a series of six young patients with psychotic symptoms satisfying the research diagnostic criteria. After intravenous injection of 11C-glucose obtained through a photosynthetic process, the regional activity of 11C in brain was measured with a four-ring positron camera. Regions of interest were obtained from computed tomographic images. Each patient underwent a second positron emission tomographic examinations after 4-5 weeks of treatment with a neuroleptic drug. No evidence of a hypofrontal pattern was found, but after treatment there was a reduced frontal uptake on the left side compared with temporal regions. The left-right asymmetry in the lentiform nucleus was reduced after treatment. ER -