TY - JOUR T1 - Stereotaxic lesion as a model of brain edema. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 722 LP - 724 VL - 4 IS - 3 AU - S E Cronqvist AU - G Kullberg Y1 - 1983/05/01 UR - http://www.ajnr.org/content/4/3/722.abstract N2 - Repeated computed tomographic (CT) examinations after thalamotomy showed a lesion vrying in size over time. This variation was interpreted as indicating presence of an edema. The effect of steroid treatment upon such an edema was tested in a pilot study of 28 patients, 16 of whom were given betamethasone. The diameter of the lesion as observed on CT was used as a measure of the amount of edema. The mean diameter was significantly lower in the steroid-treated group as compared with controls (p less than 0.01, Mann-Whitney U test). The groups were comparable with respect to other variables that might influence lesion size. It is concluded that steroid treatment has an edema-preventing effect. ER -