PT  - JOURNAL ARTICLE
AU  - L G Hutchins
AU  - H R Harnsberger
AU  - C W Hardin
AU  - W P Dillon
AU  - W R Smoker
AU  - A G Osborn
TI  - The radiologic assessment of trigeminal neuropathy.
DP  - 1989 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1031--1038
VI  - 10
IP  - 5
4099  - http://www.ajnr.org/content/10/5/1031.short
4100  - http://www.ajnr.org/content/10/5/1031.full
SO  - Am. J. Neuroradiol.1989 Sep 01; 10
AB  - The clinical and radiologic records of 76 patients with trigeminal neuropathy and an abnormal imaging study (CT and/or MR) were analyzed retrospectively. The trigeminal nerve (cranial nerve V) was divided into proximal (brainstem, preganglionic, gasserian ganglion, and cavernous sinus) and distal (extracranial V1, V2, and V3) segments. Lesions were organized according to segments and correlated with the type and distribution of clinical symptoms or signs. The purpose of the study was to (1) determine the efficacy of clinical localization of cranial nerve V lesions, (2) compare CT and MR for cranial nerve V imaging, (3) develop an MR protocol for effective cranial nerve V imaging, and (4) construct a differential diagnosis by anatomic segment for lesions of cranial nerve V. Clinical localization was found to be extremely inaccurate. CT was not as sensitive as MR for lesions involving the basal cisterns and skull base and will not detect the most common brainstem lesions (small infarcts and multiple sclerosis plaques). The MR protocol developed does not rely heavily on clinical localization. On the basis of lesions found in this series, a differential diagnosis by segment was developed. Patients with cranial nerve V symptoms should undergo MR imaging according to the protocol provided in this article. CT is not as effective as MR in imaging some cranial nerve V segments. Clinical localization is inaccurate.