%0 Journal Article %A S Shintani %A S Tsuruoka %A T Shiigai %T Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction. %D 1997 %J American Journal of Neuroradiology %P 1905-1908 %V 18 %N 10 %X We describe four patients with cerebral infarction and 99mTc-hexamethylpropyleneamine oxime (HMPAO) hyperfixation in distributions corresponding to the infarctions seen at CT and/or MR imaging. Increased HMPAO extraction due to hyperpermeability across the blood-brain barrier and increased retention due to reduced back diffusion of the tracer probably accounted for the increased fractional fixation in infarcts seen in our patients. %U https://www.ajnr.org/content/ajnr/18/10/1905.full.pdf