PT  - JOURNAL ARTICLE
AU  - R A Bronen
AU  - K P Vives
AU  - J H Kim
AU  - R K Fulbright
AU  - S S Spencer
AU  - D D Spencer
TI  - Focal cortical dysplasia of Taylor, balloon cell subtype: MR differentiation from low-grade tumors.
DP  - 1997 Jun 01
TA  - American Journal of Neuroradiology
PG  - 1141--1151
VI  - 18
IP  - 6
4099  - http://www.ajnr.org/content/18/6/1141.short
4100  - http://www.ajnr.org/content/18/6/1141.full
SO  - Am. J. Neuroradiol.1997 Jun 01; 18
AB  - PURPOSE To test the hypothesis that focal cortical dysplasia of Taylor (FCDT) can be distinguished from low-grade tumors by means of clinical and MR findings.METHODS We examined 10 clinical and 19 MR imaging variables in patients who underwent surgery for intractable epilepsy over an 8-year period. The 54 patients with low-grade glial neoplasms were compared with the eight patients who had balloon cell FCDT.RESULTS Statistically significant differences were seen with respect to eight of the MR variables and none of the clinical variables. MR findings suggesting dysplasia rather than tumor included the presence of gray matter thickening associated with a homogeneous hyperintense signal in the subcortical white matter that tapers as it extends to the lateral ventricle. A frontal lobe location favors dysplasia, while a temporal lobe (especially medial temporal lobe) location is more suggestive of a neoplasm.CONCLUSION Several MR features help distinguish balloon cell FCDT from neoplasms, especially cortical thickening and a tapered signal to the ventricle. This distinction is important for surgical planning, as the decision to operate and the extent of surgical resection often depend on the presence or absence of neoplastic tissue.