TY - JOUR T1 - Myelography with metrizamide: effect of contrast removal on side effects. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 498 LP - 501 VL - 7 IS - 3 AU - Y Numaguchi AU - A M Weems AU - A Mizushima AU - J Keating AU - A B Rege AU - F J Mather AU - J C Rice Y1 - 1986/05/01 UR - http://www.ajnr.org/content/7/3/498.abstract N2 - Moderately severe side effects, such as prolonged headache, nausea, vomiting, or psychoneurologic symptoms, were noted in 27 (32%) of 84 patients in whom the contrast medium was not removed. Conversely, among 73 patients from whom 20-25 ml of cerebrospinal fluid with the contrast medium was removed, only 10 (14%) experienced adverse effects, a statistically significant reduction. Although new contrast agents, such as iohexol and iopamidol, are reportedly less toxic than metrizamide, the contrast-removal technique described here may be indicated when large amounts of any contrast medium are used. ER -