RT Journal Article
SR Electronic
T1 Experimental Staphylococcus aureus brain abscess.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 395
OP 402
VO 7
IS 3
A1 D R Enzmann
A1 R R Britt
A1 W G Obana
A1 J Stuart
A1 K Murphy-Irwin
YR 1986
UL http://www.ajnr.org/content/7/3/395.abstract
AB The virulent organism Staphylococcus aureus produced brain abscesses that were quantitatively and qualitatively different from those caused by less virulent organisms. S. aureus abscesses created larger lesions, as earlier ependymitis, delayed progress toward healing, and caused areas of inflammatory escape outside the collagen capsule. Imaging tests revealed similar findings: the abscesses were larger, had more extensive central necrosis, and showed earlier evidence of ependymitis. This virulent organism also demonstrated that white matter is more susceptible than overlying gray matter to destruction by infection. The pattern of spread and other histologic findings suggest that collagen capsule formation has less of an infection "containment" function than was previously thought.