PT  - JOURNAL ARTICLE
AU  - J.J. Gemmete
AU  - S.K. Mukherji
TI  - Trastuzumab (Herceptin)
AID  - 10.3174/ajnr.A2619
DP  - 2011 Aug 03
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2011/08/04/ajnr.A2619.short
4100  - http://www.ajnr.org/content/early/2011/08/04/ajnr.A2619.full
AB  - SUMMARY: Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.